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Theoretically, the Cav-1 matches the dimensions and the stoichiometry of α-HL for a possible, facile assembly of its β-barrel, thereby; Cav-1 can act as an anchor for the α-HL beneath the cell surface through protein-protein interactions.
In the beginning of the decade, it was shown that MreB of B. subtilis forms helical structures beneath the cell surface and that these structures are required to maintain cell shape (Jones et al, 2001).
Then, after a delay of 30 120 s, membrane area begins to decline as a result of endocytosis until more than 50% of the plasmalemma is removed into vesicles just beneath the cell surface (Lariccia et al., 2011).
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DOI: http://dx.doi.org/10.7554/eLife.02184.004 10.7554/eLiFigure84.005 Figure 2 figure supplement 1. Immunodecoration of ESCRT-III proteins beneath protrusions from the cell surface.
According to the description of mitosis in Leadbeater's canonical book in the field, "The flagellar and non-flagellar basal bodies separate, the latter moving towards the cell surface just beneath the plasma membrane.
As this labeling does not distinguish between GLUT4 molecules localized at the cell surface or just beneath, we expressed ectopic GLUT4 in 3T3-L1 adipocytes bearing an HA-epitope tag within its first extracellular domain.
Touching the cell surface induced localized depolymerization of microtubules to form a microtubule-depleted zone surrounding a dense patch of GFP-tubulin beneath the needle tip.
Beneath the capsule is a proteinaceous S-layer, composed of two paracrystalline proteins (extractable antigen 1 [Eand and surface array protein [SAP]) that cover the bacterial cell surface [16].
However, as seen by histochemistry type VII collagen is localized solely beneath the surface epithelial cells and therefore – in contrast to α1(IV) specifically reflects alterations along the epithelial BM.
Cad99C/protocadherin 15 and Crinkled/myosin VIIa localize to microvilli/stereocilia. Sans localizes to vesicles beneath the apical surface of cells.
Histopathological analysis of paraffin embedded sections of transgenic eyes expressing either DVAP-WT or DVAP-V260I confirmed the degeneration of cells beneath the external surface of the eye (Fig. 7B).
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