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benchmark dose.
Alternatively, the benchmark dose (BMD) [44, 45] method can be employed.
Additionally it is also a prerequisite for estimating a benchmark dose.
In addition, the log-logistic model often implied a more conservative benchmark dose.
The softwares by Kalliomaa and by the U.S. EPA offered the best opportunities for benchmark dose modelling of continuous data.
Overall, benchmark dose analysis estimated a BMDL of 1857 mg/kg/day based on increased serum ALT.
These models were used to calculate benchmark dose values.
Results were also compared using benchmark dose (BMD) methodology.
The benchmark dose results obtained are in accordance with recent data on toxicity in experimental models.
Standardizing benchmark dose calculations to improve science-based decisions in human health assessments.
Regulatory agencies have increasingly relied upon calculation of benchmark dose levels from dose-effect relationship.
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