Sentence examples for benchmark compounds from inspiring English sources

Benchmark compounds 30, 35, and 36 were found to be potent against the enzyme.

The lowest exchange rate (i.e. the critical value of α [αcrit]), which suppresses a coagulation event for a given trigger scenario, was calculated, and comparisons of the different αcrit values for the study drugs were a useful model output to benchmark compounds and dosing schedules (Results, Figure 3).

Compound 12a, with IC50 <0.41 μM and SI >81.2, was the most promising compound and selected as the benchmark compound for further optimization.

We tested the copper chelators trientine, penicillamine, and bathophenanthroline for their ability to mobilize brain Aβ as measured against our benchmark compound bathocuproine (BC).

When compared with benchmark delivery compounds, the peptides are shown to have low toxicity and are highly effective at mediating gene silencing in adherent MCF-7 and A549 cell lines, primary human umbilical vein endothelial cells and both differentiated macrophage-like and suspension monocyte-like THP-1 cells.

Furthermore, we characterized the assay using six benchmark cytotoxic compounds and compared IC50 values for 3D and 2D cultures.

For benchmarking Hreed, compound and reaction information from the global reconstruction human metabolic model, Recon version 2.02 (6), was used for comparison.

Previous uses of MBMA appear in the literature such as benchmarking a compound (post-study) against a field of competitors and powering a confirmatory trial against an expected result from an active competitor.

To illustrate the use of these methods, SmAS maps and SmALI values were employed for characterizing the SAR of three benchmark sets of compounds screened with different target families.

Using concentrations within one order of magnitude of a human-health benchmark to identify compounds that may warrant additional monitoring is therefore consistent with various state and federal practices.

One weakness of benchmarks is that compounds are evaluated individually, whereas real life exposure scenarios involve multiple exposure routes and multiple compounds acting upon target organs and/or systems.