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Although researchers have demonstrated that reciprocal validation can be achieved using different patient cohorts and microarray platforms[18], few benchmark analyses have been carried out until recently to confirm the feasibility of re-using datasets obtained from different platforms for diagnostic models.
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New input for the benchmark industry code used for these analyses have developed but need to be adjusted and validated based on comparison with existing experimental data.
In real-life clinical practice, routine laboratory measurements could be used for benchmarking, provided the laboratories performing the analyses have suitable accredited quality assurance programmes, e.g. for HbA1c measurement [ 36].
Quantitative economic and environmental impact analyses have been employed to benchmark CEBC's novel technology concepts against conventional processes and to guide research and development.
For example, pathway-based toxicogenomic analyses have found substantial correlation between transcriptional benchmark dose (BMD) values from subchronic studies and those for apical non-cancer and cancer endpoints (Thomas et al., 2012b).
Benchmarking of hospital results needs to consider the case mix and the injury pattern, and scientific analyses have to deal with the comparability of study groups.
Other analyses have yielded similar numbers.
He acknowledged that such analyses have limitations.
Benefit-cost analyses have indicated that the returns to preschool programs with standards that are much stricter and more costly standards than set by our benchmarks far exceed their cost.
Systematic reviews and meta-analyses have been used to derive quality improvement benchmarks [ 77], and our present study provides literature-based estimates of readmission to the ICU and hospital mortality that could be used by institutions to select potential benchmark values.
Both organizations have compared data and ideas through two kinds of benchmark analyses.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com