Sentence examples for ben associated from inspiring English sources

Importantly, p16ink4a expression has previously ben associated with improved survival in colorectal tumours (Esteller et al, 2001; Lyall et al, 2006; Mitomi et al, 2010) but the mechanisms through which p16ink4a expression influence cancer outcome are not yet established.

The finding by Grollman et al. of AA-derived DNA adducts in renal cortical and urothelial tumour tissue of patients with documented BEN, associated with the dominance of the A T → T A transversions in the p53 tumour suppressor gene mutational spectrum, was a breakthrough in the identification of AA as an aetiological agent of the upper tract malignancy observed in BEN [ 64].

Why could a maternal history of BEN be associated with a higher risk of BEN?

A maternal history of BEN was associated with a significant increase in systolic blood pressure of 6.7 mm Hg, paternal BEN with a non-significant increase of 3.2 mm Hg, and both parents affected, a significant increase of 9.9 mm Hg.

These results demonstrate that presumably OTA-related DNA adducts do not play a key role in CHN or CHN-associated UUC [ 52, 55] and consequently in BEN and associated UUC.

A maternal history of BEN was associated with an increase in systolic blood pressure of 6.7 mm Hg (p = 0.03); paternal BEN, +3.2 mm Hg (p = 0.35); or both parents affected, +9.9 mm Hg (p = 0.002).

Unexpectedly, a maternal history of BEN was associated with average increased systolic blood pressure in offspring.

In addition, we found that, in offspring, maternal BEN is associated with increased systolic and pulse pressure.

This hypothesis implies that BEN, CHN and AAN are the same disease [ 57] and that dietary ingestion of AA, in conjunction with individual genetic susceptibility, accounts for all epidemiological, clinical and pathophysiologic features of BEN and associated UUC [ 58].

A maternal history of BEN was associated with an increased systolic blood pressure in offspring of 6.7 mm Hg (p = 0.03), and when both parents had BEN, an increased systolic blood pressure of 9.9 mm Hg (p = 0.002).

Thus, although both OTA and aristolochic acid have been demonstrated to nephrotoxic in animals, the specific pathology of BEN and associated urothelial cancers in humans has been demonstrated to be more closely reflective of that induced by aristolochic acids.