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The outcome measures in the study (see below) will be assessed before and after the post-surgical intervention period.

All the measures listed below will be assessed at the baseline t 0, and during the eighth week (t+2), the sixteenth week (t+4) and the twenty-fourth week (t+6) of the 6-month adapted rehabilitation program.

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These will each be described below.

The objectives of the project and the different constructs (explained below) that will be assessed within the DUQuE project can be illustrated as follows.

At each session, a clinical assessment will be conducted using the rating scales listed below, and treatment side effects will be assessed and rated for severity.

We will use below described validated outcome parameters, which will be assessed by means of questionnaires.

We will use the below described validated outcome parameters which will be assessed by means of questionnaires.

Below, the performance of the model will be assessed with respect to analysis in which the stress effect is not considered.

Exclusion criteria are autism, post traumatic stress syndrome, specific anxiety disorder, obsessive-compulsive disorder and an IQ below 80. Medication is allowed and will be assessed during the measurement waves.

Cost-effectiveness will be assessed using the methods below.

Finally, program adherence will be measured in terms of completed film-based lectures and exercises (see below), and respondents' activity at the Drugsmart website will be assessed.

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