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All further analyses below were conducted on the 25-item scale.
The analyses mentioned below were conducted on the total study population (n = 210).
All analyses below were conducted on a net sample using complete case analysis (n=275).
All analyses described below were conducted on a voxel-by-voxel basis using in-house software packages written on MATLAB (The MathWorks).
These analyses (and all those reported below) were conducted on the data aligned to the onset closure alignment point (Fig. 1 a).
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To facilitate model comparison, the analyses reported below are conducted on the 420 participants who supplied data at baseline and at least 1 follow-up.
In addition, sensitivity analyses using other scenarios listed below were conducted to evaluate the potential impact on the cost-effectiveness results: Using the Framingham lipid risk equation in place of the Framingham BMI risk equation Changing the discount rate from 3% to a range of 0%5%% Running the analysis with pharmacy costs only and removing cardiometabolic costs.
All exploratory factor analyses (EFAs) described below were conducted only on surveys that were at minimum 80% complete to minimize imputation error.
All in vitro studies on the HT-29 cells described below were conducted in the same concentrations of compounds, such as were used in antiproliferative activity tests.
Statistical analyses described below were conducted using R software [49].
For strain rates below 1 s−1, compression tests were conducted on an MTS loading machine, while higher strain rate tests were performed using a split Hopkinson pressure bar (SHPB).
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