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Because a decrease of oxygen concentration below the physiological threshold (1 5%) induces a metabolic shift from oxidative phosphorylation towards anaerobic glycolysis with the consequent diminution of mitochondria activity (revised in [25]), we assessed the mitochondrial activity of IhNSC cultured at different oxygen conditions and correlated it with the apoptotic score.
Values below the physiological threshold, Φ = 0.8, fail to exhibit the normal-range deformation of the substrate, 0.143 0.0954 mm at 200 seconds of simulation).
FCDs below the physiological threshold have been described in arthritical, degenerated or unhealthy cartilage [ 41]; therefore, tissue deformation under these conditions would be impaired in agreement with our computational observations.
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Solvent-only-treated mice failed to develop elevated TEWL values above the physiological threshold (A).
Such traits do not form below a "physiological threshold" [24] or "phenotypic realization threshold" [27] but vary continuously along a range of expression once the threshold is exceeded.
Below, we outline the physiological bases of both phenomena.
Thus, Wnt ligands could maintain residual activity without CRD interaction, which might be sufficient for a physiological response in vivo, although below the detection threshold of an in vitro Wnt reporter assay.
It should thus discriminate well a successful (below the threshold) from a failed (above the threshold) balance recovery.
Still, the test result fell well below the state threshold for closing the beach.
In 2009, the average London property cost £302,411, just below the IHT threshold.
Even the extremely rare case of a six-child family is still below the £500 threshold.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com