So, even if the vector populations in the places where people spend most of their time are reduced below the local threshold for infection to be endemic, a large vector population in an area that all hosts pass through regularly may be sufficient to ensure continued transmission.
Of the remainder, about half were very dim voxel clusters, below the local threshold established by NeuronStudio, but just detectable by the human operator (e.g., double red circle, Fig. 6E and white arrow, Fig. 6F), while the rest were judged actual false positives.
These are all expensive solutions, but they don't seem nearly as expensive when you consider that under the Congressional Biggert-Waters Flood Insurance Reform Act of 2012, those who have houses that sit four or more feet below the local sea level threshold, or "base flood elevation," as FEMA refers to it, could have annual premiums rise to as much as $9,500 a year — for flood coverage alone.
An attempt to explain the thermal sensitivity is lowering of the thermal threshold below the local temperature by sensitizing inflammatory mediators.
Under these conditions it is found (Barton 1979; Turelli and Hoffmann 1991; Lewis and Kareiva 1993) that the transgene will invade provided that the local invasion threshold,, is below 0.5 and that the resulting invasion wave has (asymptotic) speed proportional to the product, where D is the diffusion coefficient.
The results showed that the appropriate threshold is slightly below the local background intensity.
The reproductive rate is regulated by r, and a (which is a function of space and time, derived below) is the local critical density or Allee threshold that determines if population growth is positive or negative (Fig. 1A).
As described below, there are three types of binarization methods: global thresholding, local thresholding, and optimization-based methods.
16, 17 Settings exist somewhere in most nations of equatorial Africa where optimal conditions for propagation of malaria parasites (R0 approaching 10,000, entomologic inoculation (EIR) approaching 1,000) necessitate 99.99% control to push reproductive numbers below the threshold at which local extinction occurs (R0 < 1).
The stability of the numerical solution is maintained and the accuracy is controlled by keeping the local error below a given threshold using PI-control.
Firstly, we focus on the comparison of using only the most significant variants passing Bonferroni correction versus using all variants below a certain local fdr threshold.
