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Among women using CVM, at least eight out of ten had risk score values below the defined "high-risk" thresholds.
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At least eight out of ten middle aged women using cardiovascular medication in 2008 had cardiovascular risk scores (Framingham, SCORE, NORRISK) below defined "high-risk" thresholds ten years before.
Genotypic combinations are used to define high risk and low risk strata for the one-dimensional predisposing risk factor.
The rest of the patients were defined as high risk.
Sensitivity was defined as the probability that a patient having low expression of 14q32.31 miRNA (below the cutoff) to be in the high-risk group and specificity as the probability that a patient with high expression of 14q32.31 miRNA (above the cutoff) to be in the low-risk group.
When the frequency of the high-risk group was higher than the disease risk, sensitivity reached around 80% but PPV remained below 50% when AUC was 0.82.
In our analysis, we defined the top scoring 10% on the risk score as the high-risk group.
The president did not define "high".
It is the ultimate high-risk opportunity.
Is the research high-risk?
"These are the highest high-risk people.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com