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The selected toxin concentrations were either within or below the affinity range of these toxins for their respective cell surface receptor [32] [36].
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As in synapse formation experiments, 6, 8, 15 our model did not produce synapses below this critical value of BCR/Ag affinity, thereby matching the experimentally observed affinity range of synapse formation.
Quinidine, however, was less effective as an inhibitor and did not fit this regression line; consistent with its Kow, which is below the Kow range for high-affinity P-gp substrates.
Like those for IR-A, both analogues displayed low binding affinities for IR-B (0.27% for [AibB8]-insulin and <0.05% for [ NMeAlaB8]-insulin), and their binding affinities for IGF-1R were below the measurable range (<0.01%).
Leu-zipper dimerization increases the affinity into the subnanomolar range.
Dimerization through a Leu-zipper further increases the affinity into the subnanomolar range.
For FcεRI, the affinity is in the range of Ka~10/M.
Infrasound waves range from about 0.5Hz to 18Hz, below the audible range of humans.
It was much below the normal range".
The levels of creatinine was slightly below the normal range.
Bold data indicate that they are below the normal range.
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