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Considering the half-life of rapalogues (see below), maximal mTOR inhibition may be achieved using continuous daily oral dosing of everolimus, whereas temsirolimus that is slowly biotransformed into sirolimus can be given intravenously only once a week.
Muscles were incubated (0 120 min) with a DOX concentration range of 50 175 μ M, being below maximal plasma concentrations reached in clinical practice (Delgado et al, 1989).
All daily quality controls of the Rb elution were passed with Sr and Sr breakthrough values well below maximal allowed limits (<6% of the allowed Sr/Rb limit of 20 × 10 6 and <1.7% of the allowed Sr/Rb limit of 200 × 10 6).
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At arterial pressures 95 mmHg and below, the maximal concentrations at x = 2 mm are approximately 500 mM, over a three-fold increase of the input concentration of 150 mM.
Tumour and plasma concentrations however were far below their maximal values.
Starting from a single null divertor (SND), a sequence of desirable SF configurations can be realized whereby the PF-coil currents are below the maximal design limits.
Such resource reservation schemes inevitably result in poor resource utilization, as the actual workloads of tenants are usually below their maximal workload expectation described in their SLOs.
High batch-to-batch reproducibility can be obtained with exponential feeding profiles F t) corresponding to specific growth rates μset well below the maximal specific growth rate μmax of the organism.
Theorem 3.6 shows that for (nge 3), (nne 4) the set of the dimensions of the groups that can act properly on (X) has a lacuna of size linear in (n) located immediately below the maximal possible dimension.
Our goal is to maximize the spectrum efficiency of the SU by jointly optimizing sensing time, subchannel allocation, and transmission power, subject to the constraints that the detection probability is above the lower limit (Q_{d}^{text {min}}), the total power of SU n is below the maximal power (p^{text {max}}_{n}), and one subchannel is only allocated to one SU.
A directed 1-forest – most commonly called a functional graph (see below), sometimes maximal directed pseudoforest – is a directed graph in which each vertex has outdegree exactly one.
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