With metronidazole treatment, levels of BV-associated bacteria declined below detection thresholds and the participant was clinically BV negative at 1 month.
First, genes that are detectable (positives: above detection threshold) and not detectable (negatives: below detection threshold) were determined for each tissue according to detection thresholds defined by each manufacturer (see Methods for detailed descriptions).
These may, in real experiments, well lay below the detection threshold and thus not appear in the data [ 4].
Regarding the inflammatory markers in the CSF, all markers except the proinflammatory marker MCP-1 were below the detection threshold and even MCP-1 was very low.
Similarly, increasing K 3 to 0.41 reduced the response in Y2* to 0.07 (below the detection threshold) and decreasing K 3 to 0.004 increased the response in Y2* to 0.26.
The C2P® assay was performed on 189 frozen samples (see Additional file 1); in 18 cases, the CDK expression levels were below the detection threshold, and these cases were excluded from the analysis (assay success rate =90%).
C2P® assay measurements were performed on 189 frozen samples; in 18 cases, the CDK expression levels were below the detection threshold, and these samples were excluded from the analysis.
More than 90percentt of control subjects showed PCB 28 and PCB 101 levels below detection threshold, whereas most of the exposed subjects showed detectable blood levels of these congeners (p < 0.001, Fisher's exact test; see Table 1).
After exclusion of genes with missing spots, spots of poor quality, genes that did not dye swap, and genes below detection threshold, gene profiling was performed over the lifespan of each individual clone.
