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The formula P E3) (see below) calculates the RMNE probability assuming exactly three allelic dropouts at two or three of the analyzed loci.

An example of an optimal matrix is given below, calculated using gradient descent algorithm as described in Subsection 4.2.

The heat flux in the cut-bar apparatus is the average of the heat fluxes from Equation 14 below, calculated from the temperature differences between the upper and lower copper bars: Figure 6 Heat flux paths in the steady-state measurement method reported in Sobhan et al. [14].

We train the RF classifier using 27 features (defined below) calculated at each pixel.

This solution was characterised by a total radioactivity of 22.55 DPM/ml (determined as described below), calculated according to the counting of 10 ml of this solution.

Given the survival differences between treatment arms, presented below, calculated power estimates for the included 191 patients are 75%and97%7%, respectively for the 1-year and 2-year survival.

Using these data, the linear equation below calculated the number of patients who would have access to each of the drugs in the next five years, if no government use licenses had been granted.

Individual thalamic volume could be estimated by scaling the reference mask volume by the mean Jacobian determinant (a voxelwise measure of volume change between each image and the template, described below) calculated within the mask.

In bilaterally operated STN-DBS patients, mean implantation depth for the final electrode was 2.3 mm below calculated target depth for the left STN and 2.6 mm for the right STN (p = 0.23).

The results per nucleotide are used to calculate the NXScore for any given region, as shown below: Calculating the NXScore per nucleotide depends on the density of NXRs in the 147 bps neighborhood of that nucleotide, however to fine tune our score calculation we specifically evaluated the weighted density of NXRs in the neighborhood.

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