where γ ∗ is a fixed cutoff fade depth.
For fragments longer than D, the function used a fixed cutoff C = K × D + M.
Traditionally, a "contact" would use a fixed cutoff distance, and if two atoms were within this cutoff, they would be considered in contact.
The use of cutoff distance in these models simply serves to measure the local packing density (Halle, 2002) which is the counts within a fixed volume (consequently a fixed cutoff distance).
We write (i, j) ∈ P X as shorthand for P X (i, j) ≥ p min (X ∈ { T, Q}), where p min is a fixed cutoff probability.
The iGA algorithm works iteratively and therefore does not require a fixed cutoff of the sorted correlation list, no minimum correlation has to be defined.
All the above mentioned measures are threshold-dependent i.e. the prediction performance is evaluated for a fixed SVM cutoff score or threshold.
It seems that such an approach is more appropriate and rational than simply trying to establish a fixed diagnostic cutoff value that neglects serum protein variations.
Secondary outcomes were remission (defined as having a symptom score below a fixed threshold) and post-treatment depression scores.
Nonetheless, the improvement in reclassification for cardiovascular death was corroborated by the use of IDI, a method with no fixed cutoffs for risk categorization (13).
