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Here we show that 3-bromopyruvate (3BP), a potent novel anti-tumour agent believed to function primarily by blocking energy metabolism, differentially inactivates human SHMT1 and SHMT2.
During murine embryogenesis, GLI1 and GLI2 are believed to function primarily as transcriptional activators while GLI3 is believed to function primarily as a transcriptional repressor [6], [7].
EWS-FLI1 is believed to function primarily as an aberrant transcription factor.
This is under the control of BUB1, believed to function primarily on the mitotic spindle checkpoint.
Although CyPA was initially believed to function primarily as an intracellular protein, recent studies have revealed that it can be secreted by cells in response to inflammatory stimuli.
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Plasma gelsolin, primarily secreted by myocytes, is believed to function as an important actin scavenger in the circulation [ 6- 8].
Initially, resveratrol was believed to function as an antioxidant.
Mr. Wire, 53, said in a telephone interview that he would continue to function primarily as Genesco's chief financial officer.
The periaqueductal gray appears to function primarily in pain suppression, a result of its naturally high concentrations of endorphins.
For West, these questions don't arise, since beyond its scholarly value he understands F1 to function primarily as a simple, universally recognised luxury item or status symbol.
Years ago, ports used to function primarily as landlords providing space for companies to conduct their industrial activities, Egbertsen explained.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com