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This intron is believed to attenuate expression of the SFRS1 gene through regulated unproductive splicing and translation (RUST) mechanism [27].
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The blockade of this cascade is believed to attenuate signs of physical opiate withdrawal.
Regular physical exercise is believed to attenuate age-related reduction in large arterial elasticity [ 41].
Second, intravascular fluids are believed to attenuate the direct toxic effect of contrast agents on tubular epithelial cells.
An increase in the effects of pro-inflammatory cytokines is believed to attenuate the benefits of chemotherapy and to result in a poor outcome.
To improve the safety of MeCP2 gene therapy, the gene expression cassette was modified to include more endogenous regulatory elements believed to modulate MeCP2 expression in vivo.
Interestingly, GADD45B is believed to stimulate BGN expression [ 30].
Figure 3B shows that MAFG silencing leads to attenuated expression of GCLC, NQO1, SLC7A11, TXNRD1 (all ARE genes).
Thus, RBS substitution and start codon replacement were carried out to attenuate the expression of argF.
To avoid the drawbacks of growth disturbance due to disruption of ArgF, strategies were adopted to attenuate its expression.
This establishes negative feedback loops to attenuate HIF expression.
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CEO of Professional Science Editing for Scientists @ prosciediting.com