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It is believed that activation of the trigeminovascular system follows aberrant cortical activity, such as cortical spreading depression (CSD), epileptic discharge, or following an external electromagnetic stimulation, which stimulate trigeminal nociceptive meningeal nerve endings [ 3].
It is believed that activation of these processes by chronic viral infection can, under certain circumstances, promote tumour cell invasion and metastasis.
It is believed that activation of dislocation plasticity is beneficial to retain fracture strength of TMB2s based materials at high temperature, since plastic deformation can release elastic energy accumulated in the material and then fracture is suppressed.
It is believed that activation of Nrf2 would inhibit TGVS ability by down-regulating nNOS and c-Fos expression.
It is commonly believed that activation of the trigeminal nerve system and subsequent release of CGRP from trigeminal fibres, which leads to vasodilation within the meninges, plays a crucial role in the development of migraine attacks.
Pickens et al. [ 33] also believed that activation of CCL19 stimulated the production of VEGF.
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He believes that activation of an Amber Alert beyond reasonable distances is unnecessary because kidnappers will realistically not be driving over the speed limit.
So, taken all these observations together, it is plausible to believe that activation of other MAPK upstream targets may occur in CRC and, eventually, in other gastrointestinal cancers.
In ICCs, it is believed that the activation of calcium-activated chloride channels produces a pacemaker potential [ 11].
It is generally believed that slow activation of hERG starts from outward translation of the positive charged residues in S4 voltage sensor across the membrane field upon changes in membrane potential, which in turn causes opening of an activation gate involving S6 domains [28,37,41].
Dr. Christoph Westphal, Sirtris's chief executive, replied to this objection with a question, "Is it too good to be true that when you are young you get no disease?" Dr. Westphal said he believed that the activation of sirtuins was what kept the body healthy in youth, but that these enzymes became less powerful with age.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com