We believe carefully designed multiplexed selection methods, when complemented with high-throughput downstream analysis and characterization assays, will yield numerous high-affinity aptamers to protein and small molecule targets, and thereby generate a vast array of reagents for probing basic biological mechanisms and implementing new diagnostic and therapeutic applications in the near future.
We have long believed that carefully regulated drilling in the Marcellus Shale might be feasible, but the state should put the city's watershed permanently off limits.
Whether a LAM-specific HRQL questionnaire would have performed similarly (or better) is unknown, because one was not available for use at the time MILES was conducted; however, it is believed that carefully developed, patient-tailored, and disease-specific instruments are likely to be more sensitive to underlying change than generic instruments [ 7].
Now, who will believe the carefully invented traumas my characters recall?
This spontaneous outpouring was an implicit challenge to Vietnam's conservative Communist hierarchy, which believes in carefully choreographed political expression organized from the top down.
We also believe that carefully drafted ethical rules allowing lawyers to handle part of a case give the legal profession an opportunity to help the courts address the ever-growing number of litigants who cross our thresholds.
The city's normally mild-mannered comptroller, Alan Hevesi, is loudly objecting to a pair of particularly foul-smelling contracts that improperly bypassed the competitive bidding process and, he believes, were carefully and insidiously crafted to benefit cronies of Mayor Rudolph Giuliani.
During the long bombing campaign named Rolling Thunder, President Lyndon Johnson personally chose targets in Indochina, believing that "carefully calculated doses of force could bring about desirable and predictable responses from Hanoi".
We therefore believe that carefully considered medicinal chemistry may reduce NSC11668 efflux as well.
We believe that carefully analyzing gene expression during co-fermentation of glucose and xylose to ethanol, using our genetically modified strains, will reveal ways to optimize xylose fermentation.
