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Of course, the opposite would be true for the evolution of a catabolic pathway where enzymes would be selected for continued degradation of nutrient "A" to subsequent waste products "B," "C," "D," etc., resulting in the earliest enzyme being "upstream" (i.e., 1 ➔ 2 ➔ 3 ➔ 4 ➔ 5 ➔ waste).
When it comes to getting older, common attitudes towards aging, like being upstream of a major rapid, speak of the potential for loss: declining health, physical loss, social loss, changes in physical appearance, declining cognitive ability, depleting financial resources. .
To some extent they lie on opposing sides of the differentiation pathway, PAX3 being upstream of MITF and MITF initiating the melanogenic cascade and differentiation.
Integration into attL results in the primary transgene being upstream; attR yields the reverse order.
Still, tRNAA has also high occurrences for being upstream to 12S (30/36), composing the following cluster: 16S_tRNAN_tRNAA_12S.
This is consistent with Ki-67 being upstream of the other components in the assembly of the perichromosomal compartment.
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Cheatham Dam is upstream from Clarksville.
The Mount Coffee Hydroelectric Plant (1966) is upstream.
Now, he said, the next quest will be upstream.
This creek was upstream from the first, and separated from it by a high waterfall.
Imbrication is upstream on riverbeds and seaward on beaches.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com