Sentence examples for being the causative variant from inspiring English sources

57K being the causative variant for AGA might be regarded as less likely as this allele is fixed in East Asia whereby the prevalence of AGA is lower in this population compared to Europeans.

Based on this and other recent studies it is likely that SNP9, rs10993994, is the causative variant in the association of MSMB with PrCa risk.

AD was in line with T1D, suggesting that the rs12708716 rs12917716 risk haplotypes (III and IV) pointed to an untyped SNP, in strong LD with both, to be the causative variant.

Rs7528684 is considered to be the causative variant of the FCRL3 region to which NFκB binds and activates B cells to produce antibody by augmenting BCR-mediating signals [ 38].

Genotyping was performed for the XM_001491331 c.2032G > A variant in the PLOD1 gene, which is supposed to be the causative variant for Warmblood Fragile Foal Syndrome type 1 (WFFS) according to the patent application [ 39] (primers and PCR conditions available from Laboklin, Bad Kissingen, Germany upon request).

First among these is that the majority of SNPs that have been identified through this approach are rarely the causative variants (9).

Strong allelic imbalance in heterozygotes implies that the observed inclusion of the cassette exon is regulated in cis, and that the identified cis-sQTL most likely is the causative regulatory variant.

Another explanation could be that the causative variants differ between populations.

However, DAE-based approaches can point out the presence of a regulatory causative variant only if the subjects are heterozygous for the causative variant (and of course for the coding SNP serving as marker).

A merge analysis, in which genotypes for all SNPs in the region are imputed, may be useful to identify the causative variant (Yalcin et al. 2005; Keane et al. 2011; Baud et al. 2013).

This provides further evidence that rs10993994 (SNP9) is likely to be the strongest causative variant.