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This brings the total to 27 distinct loss-of-function mutations reported in AAGAB (Fig. 2e), providing further evidence for this being the causative gene for PPPK1.
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This gene was then further validated to be the causative gene in this disease.
Thus npr-1 is likely to be the causative gene underlying the observed speed differences.
Therefore, the mutations were in trans and NPHS2 was the causative gene for SRNS.
The final proof that cpr is the causative gene must await disruption with site specific techniques.
Mouse Gasdermin A3 (Gsdma3) is the causative gene for dominant skin mutations exhibiting alopecia.
IGF2 is the causative gene underlying the QTL for muscle growth, fat deposition and heart weight on SSC2p [ 2].
For example, researchers recently identified what is likely to be the causative gene for features of 2q32q33 microdeletion syndrome.
ATP8A2 is the causative gene of wabbler-lethal mice, which show axonal degeneration (Zhu et al, 2012).
We subsequently revealed that ERC is a homolog of the human mesothelin gene, which is the causative gene for mesothelioma 16, 17.
We can assume that one or more of these genes may likely be the causative gene(s) associated with soybean seed protein content.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com