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But much of what has been good about working with flies is now being replicated in human stem cell research, which has the added advantage of being species-relevant.
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However, these results remain to be replicated in human fibroblasts.
These findings have been replicated in human brain tissue collected during epilepsy surgery [ 15– 17, 20, 21].
This pattern was replicated in human peripheral blood mononuclear cells with NOD1/2 mutants [ 151].
127 128 These findings appear to have been replicated in human studies.
Unfortunately, avoidance of lung injury by HFOV in animal studies has not been replicated in human preterm infants.
These results were replicated in human GBM (WHO IV) cell lines U87 and U251 (Fig. 1a and Fig. 2c,d).
Rodent human disparity increases the burden of proof that a particular finding has inter-species relevance, necessitating that certain findings be replicated in human experimental models [ 54– 54].
It is somewhat disappointing that successful experimental inhibition of NFκB in animal models has not yet been replicated in human diseases.
If this finding was replicated in human mucosal cells, it would explain the current study observation of unmodified folic acid in the portal vein.
Interestingly, these observations were replicated in human samples of both atherosclerotic lesions and circulating cells, hence proving a similar FPR2/ALX activity parameter in human samples, and reinforcing the parallels between the animal models used with the human atherosclerosis.
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