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Di-nucleotide repeats were by far the most common SSRs in our ESTs, with tri- and tetra-nucleotide repeats being present at much smaller frequencies (Table 5).
We also show that Cdc48 and Ufd1 bound the NSD substrate GFHNS, but not the control GFHStop, despite the latter being present at much higher levels than the NS reporter.
Some NPAHs are classified as "probable or possible human carcinogens" and have been identified as major contributors to the overall direct-acting mutagenicity of ambient PM despite being present at much lower concentrations than those of their parent PAHs.
We also do not test for a gene dosage effect of the HPR duplication, but this is not straightforward given the rarity of the duplication allele and the similarity at the protein level between haptoglobin-related protein and haptoglobin, the latter also being present at much higher levels than the former in serum from healthy individuals (Muranjan et al. 1998).
A total of 4740 SSRs have been found in EuroPineDB for P. pinaster; tri-nucleotide repeats were found to be the most common SSRs in EuroPineDB (55.7%), with tetra-nucleotide (12.6%) and di-nucleotide (10.5%) repeats being present at much smaller frequencies.
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In these two samples, although 3H was present at much lower mass concentrations than 14C, its radioactivity levels were similar to 14C.
This is useful in many co-immunoprecipitation studies where the bait protein is present at much higher levels than its interactors and would otherwise interfere with the detection of low-abundance interacting proteins.
Moreover, the decrease of acetate concentration after 2 months (Table 4) would not be observed if fermenting bacteria were present at much higher abundance than DIRB in the FR community.
Previous research demonstrated that in both mouse and human cleavage stage embryos, AurkC was present at much higher level than AurkB, a ubiquitously expressed mitotic kinase (Avo Santos et al., 2011; Fernandez-Miranda et al., 2011; Schindler et al., 2012; Sharif et al., 2010).
Several other groups were present at much lower diversity.
The current results show that the R46X mutation is present at much higher proportions in mRNA than in DNA.
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Justyna Jupowicz-Kozak
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