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Thankfully more studies are being powered to answer these questions.
This difference, however, was small, possibly due to sample size not being powered to look for this difference.
The larger population resulted in the study being powered to detect changes from 20 to 40% in the proportion of men referred.
This included ill defined outcomes [ 12, 15]; heterogeneity of populations and interventions [ 15]; and the majority of papers not being powered to produce a valid result [ 12].
Sample size was determined for the test of diagnostic potential being powered to detect a fair diagnostic ability of the marker (power 1- β=0.90, significance level of α=0.05), defined as an AUC of 0.7, such that a minimum of 33 patients in each group were required (Obuchowski 2000).
Similar(55)
Neither trial was powered to assess mortality effect [7].
This study was powered to find an association of at least r=0.5 to be statistically significant.
The study is powered to detect relatively large effect sizes.
Therefore, we are powered to detect a much smaller difference.
Sample size calculations are powered to detect change in A1c.
The study is powered to detect a 50% reduction at a 0.8 power.
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