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However, according to the free hormone hypothesis, despite being less efficacious in elevating total 25(OH D levels, 25(OH)D2 may be more available to exert biological activity being less tightly protein bound than 25(OH)D3.
Similar(59)
Colonoscopy may be less efficacious in reducing colorectal cancer mortality in the proximal compared with the distal colon.
Primary hepatitis B virus (HBV) vaccination through the intramuscular (IM) route is less efficacious in dialysis patients than in the general population.
MRA is less efficacious in the diagnosis of cartilage abnormalities in the hip, both femoral and acetabular.
Again, they found that adjuncts to treatment were less efficacious in preventing relapse if the patient had experienced more episodes.
This explains why CY is less efficacious in these experiments.
They reported improved long-term glucose and insulin homeostasis by CD3 antibody depletion in obese B6 mice with concomitant restoration of epididymal Tregs; treatment was less efficacious in an ob/ob model.
Indeed the Dutch WCV was shown to be less efficacious in the mouse model against Prn2 strains compared to Prn3 strains, although the difference was not statistically significant [13].
Whether this treatment is less efficacious in persons with HIV infection is unknown.
23 However, it was found to be less efficacious in relieving acute pain.
Mifepristone, however, was less efficacious in preventing escape of SK-OV-3 cells.
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