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However, according to the free hormone hypothesis, despite being less efficacious in elevating total 25(OH D levels, 25(OH)D2 may be more available to exert biological activity being less tightly protein bound than 25(OH)D3.
From the results of this survey it can be concluded that Mexican psychiatrists are aware of the advantages of SGAs in the treatment of schizophrenia, although they perceive SGAs as being less efficacious for the treatment of positive symptoms than FGAs.
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He said it was "less efficacious for the real economy than most people suppose".
He made similar remarks at a private investment conference in April, according to a summary obtained by The Financial Times, declaring that the Fed's bond purchasing "in my view is less efficacious for the real economy than most people suppose".
Platelet transfusions given to patients with fever or systemic inflammation are less efficacious.
MRA is less efficacious in the diagnosis of cartilage abnormalities in the hip, both femoral and acetabular.
Again, they found that adjuncts to treatment were less efficacious in preventing relapse if the patient had experienced more episodes.
Colonoscopy may be less efficacious in reducing colorectal cancer mortality in the proximal compared with the distal colon.
Parents with a history of smoking and parents of adolescents who had tried smoking were less efficacious, held weaker antismoking beliefs, and less often reported household smoking rules.
Counter-intuitively, there are situations in which earlier inoculation can be less efficacious, and simultaneous inoculation with antibiotics can be detrimental.
Primary hepatitis B virus (HBV) vaccination through the intramuscular (IM) route is less efficacious in dialysis patients than in the general population.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com