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Hence, the most dramatic inhibition of EGFR internalization occurred at 2 min with 60% being internalized in control cells compared with 20% being internalized in cells expressing Tom1L1/Y460F, Tom1L1/Y392F or Tom1L1/Y460F SH3.
The findings are aligned with the idea that both economic incentives and hierarchical relationships formalized in contract agreements require being internalized in working practices by means of informal and socially based mechanisms.
The efficacy of uptake appears to be similar in all cell types we have examined with mitochondria being internalized in a time-dependent manner.
On the other hand, both functionalized systems proved capable of being internalized in a brain tumor cell line (i.e., glioblastoma A-172).
As shown in Figure 7H and quantified in Figure 7I, Tom1L1 siRNA-treated A431 cells internalized about 20 30% EGFR (second panel, lane 2) compared with 50 60% of EGFR being internalized in control cells (lane 1).
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Absent ratification, through which international norms are internalized in national policies, it remains unlikely that the right to health becomes a guiding norm in U.S. health policymaking.
The amount of uPAR that was internalized in this first step was considered as 100% of the internalized receptor for quantification purposes.
PGA-Dox nanocapsules were internalized in large numbers by LIM1215 colorectal tumor cells, with most of the internalized capsules being taken up by the lysosomes.
We found that CysLT1 is internalized in a clathrin/Rab-5-dependent pathway; we also suggest that this internalization is arrestin-3-dependent.
FRα is internalized in a caveolar structure as early endosome19.
The non-sonicated α-Syn amyloids were internalized in similar percentage (Fig. 1a,b).
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