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Our alignment potential measures the log-odds ratio of one alignment being generated from two related proteins to being generated from two unrelated proteins, by integrating both local and global context-specific information.
This article has presented a novel protein threading method using a context-specific alignment potential, which measures the log-odds ratio of one alignment being generated from two related proteins to being generated from two unrelated proteins.
Our alignment potential measures the log-odds ratio of one alignment being generated from two related proteins to being generated from two unrelated proteins, by integrating context-specific local and global information.
(1) where is the background (or reference) probability of A, i.e. the probability of A being generated from two randomly selected proteins with the same lengths as S and T, respectively.
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