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Methods: In a crossover design outpatient study, 12 adults aged 24 36 years took 15 mg/kg/day (CA) or no bile acid supplement (control) while being fed a controlled diet (AHA heart-healthy diet).
Study 1 included 11 subjects 24 to 37 years of age, taking 15 mg/kg/day chenodeoxycholic acid (CDCA) or no bile acid for 20 days while being fed a controlled diet.
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Mice were fed a control diet or HFD in a pair-fed isocaloric fashion for 8 or 16 weeks.
Cows were fed a control diet during a 2-wk standardization period.
Dogs were fed a control diet without supplemental sPLA2i or an sPLA2i supplemented diet.
Rats were fed a control (C) or experimental diet containing 30% of BR.
DS rats were fed a control diet (0.3% NaCl) or high salt diet (8% NaCl) from 7 weeks of age.
All three groups were fed a control diet for 21 days prior to the start of the 90-day experimental period.
Horses were fed a control diet (40% hay, 60% concentrate) balanced to meet NRC requirements for maintenance of mature horses (NRC, Nutrient requirements of horses, 1989).
Cow's milk allergic (CMA) or BTBR male mice were fed a Control, Active 1, or Active 2 diet for 7 consecutive weeks.
Cows were fed a control diet based on corn silage (66% of DM), or the control plus 300 mL FO/d into the rumen (FO-R) or duodenum (FO-D) for 4 weeks in a replicated 3 × 3 Latin square design.
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