Sentence examples for being explored in phase from inspiring English sources

In fact, such approaches are being explored in phase III trials.

In addition there is a dramatic lack of new antimicrobial agents being explored in phase 2 or 3 clinical trials, especially for Gram-negative organisms, and development of an antimicrobial with a genuinely novel mechanism of action is estimated to take years [2].

In addition there is a dramatic lack of new antimicrobial agents being explored in phase 2 or 3 clinical trials, especially for Gram-negative organisms, and development of an antimicrobial with a genuinely novel mechanism of action is estimated to take years [ 2].

Based on preclinical models, dual inhibition of both IGF1R - with either monoclonal antibodies or tyrosine kinase inhibitors - and mTOR results in a superior antiproliferative effect over each single strategy [ 5], and this combination is now being explored in phase I/II trials in patients with breast cancer.

Targeting of stem-like cells is another strategy that has also been explored in Phase I clinical trials.

This group of patients could possibly benefit of more individualised treatments, such as selective COX-2 inhibitors, which are already approved for treatment of familial colorectal adenomatous polyposis, and started to be explored in Phase I II studies (Snyderman, 2001).

Given the schedule dependency observed preclinically, three regimens were explored in phase I studies: (1) 0.2–5.2 mg m−2 daily for 5 days every 3 weeks (McDonald et al, 1998); (2) 10 40 mg m−2 weekly for 4 weeks repeated every 6 weeks (Rinaldi et al, 1995); and (3) 50–700 mg m−2 every 3 weeks (Rinaldi et al, 1999).

Table 1 Model parameters and their range of values that were explored in Phase-I of simulation experiments Parameter Values explored Description num-agents 1000, 2500, 5000, 7500, 10,000 The number of agents in the model love-radar 1, 2, 3 The diameter of an agent's ego network through which potential partners are sought.

Three different treatment schedules have been explored in phase-I trials (Table 1).

The application of small interfering RNA (siRNA) for cancer treatment is a promising strategy currently being explored in early phase clinical trials.

PDK inhibition with dichloroacetate is being explored in a phase I trial of metabolic reprogramming therapy in recurrent HNSCC (NCT01163487).