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All animals were euthanized for analysis using procedures approved by the appropriate institutional animal welfare committee.
Mice were euthanized for analysis 6 8 weeks later (compared with 4 weeks in the former experiments).
At the end of approximately 1 year (52 weeks), these multiparous female breeders were euthanized for analysis.
All mice were euthanized for analysis by the end of the sixth week after the first injection.
At 24 h after LPS treatment, mice were euthanized for analysis of lung tissue and bronchoalveolar lavage (BAL).
On PND52 (end of chelation therapy) one animal from each litter was euthanized for analysis of blood and whole brain Pb levels by inductively coupled plasma-high resolution mass spectrometry, as previously described (Smith et al. 2000b; see Supplemental Material available online at http://www.ehponline.org/docs/2006/9263/suppl.pdf).org/docs/2006/9263/suppl.pdf
The monkeys were euthanized for histological analysis.
Survivors were euthanized for tissue analysis and microbiologic study.
Three rats from each group were euthanized for organ analysis at 2, 3, and 4 days and 4, 8, and 12 weeks postoperatively.
The survival study was terminated at day 120, at which point those mice surviving beyond that time were euthanized for post study analysis.
At day 70 post-immunization, the mice were euthanized for tissue isolation and sample analysis.
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