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All screening tests were performed within a maximum of 7 d before enrolment, with eligible patients being enroled within 7 d after completion of screening.
Building rapport with participants from the outset is crucial to reduce loss of potential participants prior to being enroled, randomised and/or booked on a course.
Many patients would, if given the choice, prefer being enroled at higher dose levels rather than at lower levels, in which the dose administered is thought to be insufficient.
Of these, 13 patients (56.5%) discontinued treatment owing to radiological progression, 7 (30.4%) owing to clinical progression and 3 (13%) owing to PSA progression exclusively before being enroled in subsequent clinical trials.
In addition, as with any technique that aims to capture data on everyday behaviours it should be acknowledged that a particular week may not be representative of an individual's normal life and/or behaviour may be altered as a consequence of being enroled in the study.
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In total, 1156 participants were enroled in the study.
In total 171 primary HCWs and 369 secondary HCWs were enroled during January to March 2010.
All randomized patients were enroled.
Nine patients with glioblastoma multiforme were enroled.
Thirty-four MS and 15 PS were enroled.
In total, 142 patients were enroled.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com