Sentence examples for being driven to fixation from inspiring English sources

Surprisingly, I find a similar fraction of amino-acid mutations being driven to fixation by positive selection in D. miranda and D. melanogaster.

Genetic drift can lead to SNPs being driven to fixation or lost entirely from a population simply by random chance (42).

Here, I estimate that a similar fraction (~50%) of amino-acid mutations is being driven to fixation by positive selection in two species of Drosophila that differ roughly 5-fold in their effective population sizes.

Analyzing nearly 100 nonhomologous X-linked loci in both species, Bachtrog estimated a similar fraction of amino acid mutations being driven to fixation by selection between the two species.

Although this hypothesis explains many features of the data, recent findings suggest that for some loci, unpreferred codons are being driven to fixation by natural selection in the D. melanogaster and the Drosophila simulans clade (Bauer DuMont et al. 2004; Neafsey and Galagan 2007; Nielsen et al. 2007; Singh et al. 2007; Holloway et al. 2008).

However, such deleterious variants are not relevant to questions of what possibilities are available for the evolution of robustness, because they will essentially never be driven to fixation if they are subject to strong negative selection.

If these dual buffering alleles are in fact exceedingly rare, as suggested by this analysis, then they would have to confer a vastly superior fitness advantage to be driven to fixation (100% frequency within a species) at higher rates than the far more common alleles buffering just one type of variation.

In one simple case, if selection is intermittent, a haplotype that is driven to fixation during one episode of strong selection may experience subsequent changes during a period of relaxed selection (these mutations may increase, decrease, or not affect resistance), in which case the eventual path taken may include non-favored and/or double mutations.

This implies that a substantial fraction of amino acid substitutions has been driven to fixation by positive selection.

If new centromere alleles are driven to fixation by meiotic drive within subpopulations, divergence between subpopulations may lead to the inference of high levels of global polymorphism.

Thus, such genes can be driven to fixation in the population even if their associated traits are slightly deleterious to the organisms carrying them.