Of all the genes detected, 4864 were identified as differentially expressed genes (DEGs), with 2613 being upregulated and 2251 being downregulated in latent buds than in prompt buds.
DAX1 shows sexually dimorphic gonadal expression, being downregulated in the developing testis [33].
Seven genes, which were identified by the array data as being downregulated, were repressed in most of the cloned embryos.
These genes may be being downregulated in a translational form and the upregulation of the mRNA could be a retroactive mechanism to valance that.
No more GABA staining was detectable in newlyborn cells at long survival times, this neurotransmitter being downregulated as cell differentiation occurs [18].
The toxic METH challenge caused differential expression in 95 genes in the METH preconditioned group (MM), with 70 being upregulated and 25 being downregulated (Table 3).
Together these results show that expression of all Tensins is largely absent in human cancer cell lines as well as being downregulated in human kidney tumors.
The toxic METH challenge caused changes in a total of 100 genes in the absence of METH preconditioning (SM group), with 50 being upregulated and 50 being downregulated (Table 2).
In the current study a total of 28 differentially expressed miRNA were identified with 19 miRNA being upregulated and 9 miRNA being downregulated in high grade serous carcinoma versus normal fallopian tubes by microarray analysis.
Notably, the expression of serum amyloid genes (Saa1, Saa2, Saa3) was upregulated in the Hfe−/− mice compared to being downregulated in dietary iron overload, suggesting that Hfe deficiency induces this gene expression by an iron-independent mechanism.
The protein is expressed in a proliferation-dependent manner, being downregulated during transient cell cycle exit.
