Sentence examples for being dose from inspiring English sources

Results showed that inclusion of EO increased milk production per ewe, the effect being dose dependent [1.565, 1.681, 1.876, and 2.119 L/d (standard error of the difference ± 0.176) for the control, 50, 100, and 150 mg of EO/kg of concentrate diets, respectively], and thus improved feed utilization.

The MTD was defined on conventional toxicity criteria, with thrombocytopaenia and neutropaenia being dose limiting.

Cardiac: Anthracyclines can cause a cardiomyopathy, the incidence being dose related and increasing with age.

The main toxicity of TP300 was haematologic with neutropenia and, to a lesser extent thrombocytopenia, being dose limiting.

In conclusion, cardiac toxicity in this phase I study was present, but not considered as being dose limiting.

The recommended Phase II dose for this schedule was 37.5 mg m day−1, with grade 4 neutropenia and grade 3 fatigue being dose limiting.

The latter consideration stems from toxic endpoints being dose-dependent [14,15], and animal models tend to use doses higher than the equivalent human doses.

Figure 4) Significantly blocked (P < 0.05) in animals pretreated with the antagonists prazosin (α1, 10 and 30 μg/kg; Fig. 4a) or rauwolscine (α2, 100 and 300 μg/kg; Fig. 4b), with this blockade being dose-dependent and apparently more marked with rauwolscine.

Treatment with 2.0 5.0 µM AG 1478 or 50 100 µM PD 98059 inhibited the G3-induced proportional increase of cells in S, G2 and M stages, the effect being dose-related (Fig. 5b and 5c, Fig. S4 and S5).

The MTD is 150 mg m−2, with myelosuppression, particularly thrombocytopenia, being dose-limiting.

This non-platinum-based outpatient triplet showed promising activity against NSCLC with myelosuppression, in particular neutropenia, being dose-limiting.