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The mutated and original secondary structures' representing dot plot matrices are being compared using the DoPloCompare application (see 'DoPloCompare' section).
These SH tests involved optimizing each data set across the topologies being compared, using the GTR model described above, then evaluating whether the -lnL of a given dataset differed significantly between the "best" versus alternative topologies.
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Five protocols are compared using the simulator.
Groups were compared using the t-test.
The models were compared using the Deviance Information Criterion.
Measurements were compared using the Mann Whitney test.
Survivals were compared using the log-rank test.
Nonparametric variables were compared using the Mann–Whitney test.
Proportions were compared using the Chi-square test.
Continuous variables were compared using the Student's t test.
Categorical variables were compared using the X2 test.
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