Drawing on previous work by Jenkins et al. (2001) which showed that the binding site for haloalkane GAs in the GABAA receptor could only accommodate one molecule, they proposed that pressure reversal occurred when halothane aggregated, so fewer monomeric halothane was available to bind to the putative binding site.
This is because, only a very small percentage of binding sites are available to bind to interact with the transcription factors, as mentioned earlier in the limitation of regulatory networks section.
In the liver, diferric transferrin competes with TfR for binding to Hfe, and, when iron is increased, more Hfe is available to bind to TfR2; this complex, TfR2-Hfe, promotes HJV binding to BMP6, increasing hepcidin synthesis [ 34, 36].
Up to that date, normally two years after manufacture, all the fluoride must be available to bind to tooth enamel, hardening it against the acid that causes cavities.
These data are reasonable, indicating the presence of many active sites on LL and LA surface, which are available to bind with Cd II) ions at low concentration.
These proteins bind specifically to antibodies through their nonantigenic (Fc) regions, which allow the antigen binding sites of the immobilized antibody to be oriented away from the solid phase and be available to bind the target analyte.
Released MIF and MIF-A1-I3 complexes are available to bind to urothelial (cell-surface) CD74 and GRP78 and possibly activate a pro-inflammatory cascade in the bladder.
3) All His-tagged GFP-RyR1 fusion proteins bound to the NTA-agarose column thus indicating that the introduced His10 tags are available to bind Ni/NTA and, by extension, Cy3NTA.
Pieces of fibronectin that failed to support fibronectin assembly strongly supported cell adhesion per se, demonstrating that the RGD sequence in 10F3 of the various adsorbed proteins is available to bind integrins.
After the induction of apoptosis phosphatidylserine is translocated from the inner (cytoplasmic) leaflet of the membrane to the outer (cell surface) leaflet, phosphatidylserine on the outer leaflet is available to bind labeled Annexin V, providing the basis for a simple staining assay.
