We have also reported differences in 5mC and 5hmC between NANOG-low and -high cells, with increased expression of TET1/2 being associated with increased 5hmC in NANOG-high cells (Ficz et al., 2013).
Of these, ventilator-associated pneumonia (VAP) is one of the most severe, being associated with increased morbidity and duration of MV in the intensive care unit (ICU) [ 1, 2].
Obesity is defined as a state of increased adipose tissue of enough magnitude to produce adverse health consequences being associated with increased morbidity and mortality (2).
These studies further indicate that the association between SSB consumption and body weight is largely due to SSB being associated with increased total energy intake [ 31, 48].
The use of combined oral contraceptives is widespread among hypertensive women despite being associated with increased cardiovascular risk.
TDIs can be arbitrarily divided by anatomy into left and right diaphragmatic injuries with right-sided injuries being associated with increased morbidity and mortality [15].
The rationale behind this is that cholestasis has been described to be present in 20% of the patients during their stay in the ICU, being the most common feature of liver dysfunction and being associated with increased morbidity and mortality in this hospital ward [5, 26, 27].
In our study, only HbS was found to have an impact in the epidemiological analyses, being associated with increased gametocyte positivity and density.
Although no statistically significant associations were observed in this independent sample (P = 0.41), a trend in the same direction was observed, with the rare ENT1-216Thr allele being associated with increased risk of alcoholism with alcohol withdrawal seizures [OR = 1.69, 95% CI = (0.47, 5.99)].
Anesthesia for morbidly obese patients is generally regarded as being associated with increased risks [ 8, 14].
This acknowledged that there was a perception of chemotherapy being associated with increased toxicity in older patients.
