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The presence of EpCAM-positive, live CTCs predicts progression in individual mRCC patient, being associated with distant metastasis under first-line Sunitinib.
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A substantial divergence in the landscape of driver alterations was associated with distant appearance of a recurrent tumor from the initial tumor, suggesting that the genomic profile of the initial tumor can mislead targeted therapies for the distally recurred tumor.
Microvessel density in NSCLC is associated with distant metastatic spread and poor survival [37].
Invasion into the parapharyngeal space venous plexus and marrow of the skull base bones is associated with distant metastasis, and involvement of these anatomic sites is considered a potential route for hematogenous disease spread in patients with Stage I-III NPC.
Our study demonstrates that increased cyclin E expression is associated with distant metastases for whichever histological component of nephroblastoma it is assessed in.
Thirteen emm types are associated with distant STs: five emm types are associated with >two distant STs and eight emm types are found among a single pair of distant STs, whereas five emm types are associated with three or more distant STs (Table 4).
A hypoxic profile that included 13 genes such as VEGF and ANGPTL4, has been associated with distant metastases and might represent an independent predictor of outcomes in primary breast cancers [27].
Low expression of AR is associated with distant metastasis in the AR-positive TNBCs [ 12].
Its expression was associated with distant metastasis and local progression [ 65].
Our data suggest that αB-crystallin expression is associated with distant metastases formation in HNSCC patients.
Regarding disease progression, we found that rs13387042 homozygous variant genotype was associated with distant metastasis.
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