Sentence examples for being a substrate of from inspiring English sources
Interestingly, overexpression of synj significantly rescued mnb phenotypes, consistent with Synj being a substrate of Mnb.
In contrast, the octadecatetraenoic acid content decreased, it being a substrate of elongase, while total lipids remained constant.
However, it is also used in other cellular processes, the most notable one being a substrate of enzymes that add or remove chemical groups from proteins, in posttranslational modifications.
Controversial results have been reported concerning oxycodone being a substrate of P-gp.
JAI-51 also inhibited the activity of P-gp and BCRP, without being a substrate of these efflux pumps.
Being a substrate of the E3 ubiquitin ligase anaphase-promoting complex-Cdh1 (APFKFB3), PFKFB3 is targeted to proteasomal degradation in neurons.
Furthermore, Rab35, which is a substrate of TBC1d24, is known to regulate E-cadherin recycling in the mammalian cell lines31,55.
TDP43 contains a canonical leucine-rich nuclear export signal (NES 29,30 that is predicted to be a substrate of exportin-1 (XPO1/CRM1), a conserved nuclear export factor in mammalian cells31,32.
Recently Na-F was also found to be a substrate of organic anion transporting polypeptides (OATP), which are present in BeWo cells and placental tissue in vivo57,58,59,60.
As TRIM24 is a substrate of SPOP10,19, we hypothesized that TRIM28, through interacting with TRIM24 protein, might disrupt SPOP-mediated TRIM24 binding, ubiquitination, and/or degradation.
