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The synthesis of these new derivatives was achieved by alkylation of appropriate indanones to introduce the side chain bearing a terminal ester group, the latter being a precursor of hydroxamic acid and aminobenzamide derivatives.
The synthesis of these new analogs was achieved by alkylation of an appropriate indanone (or tetralone) to introduce the side chain bearing a terminal ester group, the latter being a precursor of hydroxamic acid and aminobenzamide derivatives.
Moreover, it is the uppermost mediator in the propagation of detrimental oxidative chain reactions, being a precursor of all other major reactive oxygen species found in biological systems, including the powerful oxidants hydroxyl radical (⋅OH), hydrogen peroxide (H2O2), and peroxynitrite (OONO−) [26], [32], [39], [91].
The characteristic of NAC of being a precursor of GSH represents the most important pharmacological property of this drug.
The formation of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) occurs after phosphorylation and decarboxylation of mevalonate, DMAPP being a precursor of all polyprenyl compounds.
Being a precursor of GSH synthesis, NAC may provide additional benefits in conditions such as COPD, where the endogenous GSH pool is depleted.
Similar(45)
It was a precursor of the stagecoach.
It is a precursor of the placenta.
In a way, it's a precursor of rap".
"In a sense, Coubertin was a precursor of that.
So our stunning display is a precursor of loss.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com