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While there is extensive evidence of CCN2 being a key mediator in cardiac fibrosis17, the role of CCN2 in MI and post-infarction remodelling remains unclear.
Our findings further strengthen the argument for IL-13 being a key mediator in the pathogenesis of AHR in asthma.
A member of this family caspase-3 has been identified as being a key mediator of apoptosis in mammalian [ 25].
Interestingly, in addition to being a key mediator that regulates cell survival, S6K is also a critical mediator of glycolytic metabolism in mTOR-activated cells [ 17].
These findings build upon a considerable body of evidence pointing to the RANK signaling pathway as being a key mediator of progestin action in the mammary glands.
Inflammation is thought to play an important role in the pathophysiology of diabetic retinopathy (DR) [ 1- 3] with elevated levels of vascular endothelial growth factor (VEGF) being a key mediator [ 4].
Similar(52)
hcnC is a key mediator of toxin-mediated killing in C. elegans [19].
Neuroplasticity accompanying learning is a key mediator of stroke rehabilitation.
Gilpin, N. W. & Roberto, M. Neuropeptide modulation of central amygdala neuroplasticity is a key mediator of alcohol dependence.
Methoprene-tolerant protein (MET) is a key mediator of antimetamorphic signaling in insects.
Superficial zone protein (SZP) is a key mediator of boundary lubrication of articular cartilage in joints.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com