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It is expressed in villous cytotrophoblasts (vCTBs), promotes proliferation and survival of trophoblastic cells and is a promising target to decipher the molecular mechanisms behind the pathogenesis of PE in more detail.
However, the molecular mechanism behind the pathogenesis of cardiac disease is unknown.
Despite the difficulties in detection, it is possible to use a murine model to study the underlying mechanism behind the pathogenesis of CT [ 19].
Indeed, evidence pertaining to this matter indicates that inflammation and its multiple components are the driving force behind the pathogenesis of these disorders.
For the past 40 years, the predominant theory behind the pathogenesis of PNI has been that tumour cells spreading along neural sheaths are privileged with low resistance (Liebig et al, 2009).
It is envisaged that these miRNAs may explain the mechanisms behind the pathogenesis of many cardiac diseases, and, most importantly, may provide new avenues for therapeutic intervention that will limit cardiomyocyte cell death before it irreversibly affects cardiac function.
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Because the discovery of anticancer medicine lags behind the rapid increase in the pathogenesis of cancer, more than 10 million people are expected to die of cancer in 2020, which corresponds to approximately 20% of all human deaths.
Our results provide novel insights into the underlying mechanisms behind matrix contraction by fibroblasts and the exaggerated TGFβ signalling observed in the pathogenesis of SSc.
75 Elucidating the pathophysiology behind monogenic forms of diabetes can help unravel some of the mysteries underlying the pathogenesis of the more common type 2 diabetes.
MTs are also implicated in the pathogenesis of arrhythmias associated with cardiac hypertrophy, although the mechanisms behind this are not clear (Parker et al., 2001; White, 2011).
The pathogenesis of the disease is still not fully understood.
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