Gene-gene interaction could be behind the observation that SLE loci show variability in effect sizes in function of the genetic background.
In that most trite of observations, after 9/11 everything changed -- right behind that for a trite observation is the accepted wisdom that, when it comes to another act of terrorism, "it's not a matter of 'if,' but "when".
The intuition behind this observation is that players who select a leader might feel more trust inside the group and choose to cooperate more (Grossman 2014 .4.
The reason behind this observation is that at and, the cosine of the angle between the and both of the vectors is 0. The vectors are at right angles to each other.
A probable reason behind this observation is that the inclusion of more conformations into a docking protocol neglects the fluctuations of docking poses and provides a more coherent binding mode for a given ligand, therefore enabling a clearer discrimination between active and inactive compounds.
Gene displacement in situ is the most probable process behind this observation given that the operon is conserved in all the cases.
One possible mechanism behind this observation is that the relatively slow (enteral) uptake of levodopa has led to dopamine autoreceptor-driven adaptation of dopamine neuronal firing (Grace 1991; Seeman and Madras 1998).
SLPI concentrations in the airways of COPD and CF patients are reduced during bacterial exacerbation, and it has been postulated that the mechanism behind this observation involves proteolytic cleavage of the protein by neutrophil elastase [ 26- 29].
Although biological experiments are necessary to investigate molecular mechanism behind this observation, we speculate that the nucleosome-free regions serve as "landing sites" for transcription factors, including Sp1, which have less precise binding motifs (which are overrepresented among broad promoters) than the TATA box [ 43- 45].
