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The similarities between sleep and anaesthesia include: a subjective loss of consciousness, reduced sensory awareness, and a reduction in behavioural responsiveness.
Behavioural responsiveness of the mice was tested following one week of habituation to the testing environment and the observer.
We constructed 10 measures for each species indicating its overall behavioural responsiveness to the presence of a neighbour.
In the short term, arousals have positive effects by ensuring a higher level of behavioural responsiveness in the presence of external stimuli, while sleep is protected as far as possible.
Like ATF4, DISC1 modulates the behavioural responsiveness to amphetamine in rodent models (66, 68, 69), and DISC1 mutations or altered expression are associated with depression-like behaviours in several mouse models (62– 62).
ATF4 expression in the nucleus accumbens (NA), a key reward region in the brain, is induced by amphetamine administration or restraint stress, and ATF4 overexpression in this region decreases the behavioural responsiveness to amphetamine (12).
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These inbred mouse strains have been used as a genetic animal model of depression-like behaviour and are characterized by a different stress-responsiveness, since DBA/2J mice display a stronger behavioural response to stressful conditions [ 22, 23, 29].
Further, stronger positive correlations between self-report BAS traits and behavioural reward responsiveness were found for participants who perceived the task as more rewarding than initially expected.
A number of studies have highlighted that attention-deficit hyperactivity disorder (ADHD) is associated with abnormalities in behavioural and neural responsiveness to performance errors.
Personality refers to individual differences in cognitive styles, behavioural dispositions, and emotional responsiveness.
Clinical responsiveness to cognitive behavioural therapy for psychosis (CBTp) varies.
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CEO of Professional Science Editing for Scientists @ prosciediting.com