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Juvenile salmonids have shown distinct shifts in behavioural phenotypes in response to GH transgenesis, including increased foraging-induced aggression and reduced antipredator behaviour (Abrahams and Sutterlin 1999; Sundstrom et al. 2003, 2004).
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The false positive rate for developmental and behavioural phenotypes observed in response to RNAi by feeding in C. elegans is <1%, thus thresholds were set for ease of scoring.
Many brain and behavioural phenotypes in humans exhibit some degree of sexual dimorphism.
mGluR5 NAMs prevent behavioural phenotypes in animal models of these disorders [ 56- 58].
Brain delivery led to an effective amelioration of the overall brain pathology and behavioural phenotype in treated MPS-IIIA mice.
In the rat, the most constant behavioural phenotypes include hyperlocomotion in response to novelty, psychostimulant sensitively, impulsivity, and augmented motivation.
All organisms are elaborately designed to change their phenotypes in response to environmental change, according to rules that evolve by prior evolution.
Rarely is the evolution of behavioural phenotypes explored in the larger context of the evolution of phenotypically plastic traits.
Further phenotypic analysis of behavioural phenotypes could prove fruitful in beginning to answer such questions.
"In particular, we are interested to see if autism-like behavioural phenotypes are revealed in these mutants.
One of the most obvious and highly penetrant motor behavioural phenotypes we observed in Tc1 mice is hyperactivity.
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