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The dissimilar behaviour of these genes in each cell type is probably a consequence of metabolic differences between muscle and liver.
There was a surprising degree of uniformity in behaviour of these genes across all conditions and time points.
We show that by manipulating the pathway and module contribution of such genes to follow underlying trends we can interpret microarray results centred on the behaviour of these genes.
Supervised clustering of the 997 transcripts present in three or more of the individual comparisons was used to assess the behaviour of these genes across the four experimental conditions.
The behaviour of these genes provides an interesting paradigm in which to study the regulation of promoters in general and, in particular, to explore how the seemingly quantitative regulation of the follistatin promoter in planarians is related to their responses when they are wounded.
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We are interested in the behaviour of these gene products with time.
This analysis was partitioned to account for the different behaviour of the genes as well as the third codon of ND2.
Only the average behaviour of the genes composing the signature indicates a clear adenoma/PTC distinction.
The duplication behaviour of the genes from which the disrupted mRNAs arise is also typical of the whole human gene complement.
The dataset was then normalized to the same expression level and clustered based on the similarities in the regulatory behaviour of the genes.
The classification of the experimental conditions, previously mentioned, was included in the expression plots through an horizontal colour line that allows to quickly associate the behaviour of the genes with the type of perturbation.
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characteristics of these genes
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com