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To investigate the frequency, treatment and clinical behaviour of differentiated microcarcinoma of the thyroid gland (PTMC).
While monocytic cell lines have obvious advantages in terms of ease of acquisition, as compared to primary macrophages, their differentiation state has meant that inferences drawn from these experiments may not always accurately predict the behaviour of differentiated tissue macrophages.
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It is a widely used cell line which resembles the behaviour of poorly differentiated thyroid tumours, including a very low iodide uptake function as well as lost of NIS and Pax8 gene expression, together with several other markers of thyrocyte differentiation [ 12].
The adopted BRB model, shown in an earlier study to give accurate predictions of the experimental behaviour of BRBs, is differentiated with respect to its material constitutive parameters using the direct differentiation method (DDM) and the obtained response sensitivities are validated by comparisons with the finite difference method (FDM).
As RO is affected by EA(a i ) and F(b i ), this provides the cognitive behaviour of retrospective effects as differentiated from prior behaviour.
Urban and suburban regions lead to attribution of differentiated public low carbon behaviour.
Based on the GSA results we postulate that by varying one or more of these parameters we can achieve a significant shift in the pathway's behaviour resulting in a new resting state typical of differentiated cells.
However, since myoblasts are mononuclear undifferentiated muscle cells, their behaviour may likely be quite different from that of differentiated muscle fibres.
Imaging of differentiated HL60 cells (which mimic neutrophil behaviour and show both plaques and cytoneme projections) expressing the filamentous-actin probe LifeAct revealed that these structures were composed of F-actin (Fig 3D).
In terms of morphological appearance and biological behaviour, poorly differentiated thyroid cancer (PDTC) represents intermediate entities in the progression from WDTC to ATC, and has an intermediate prognosis [ 4].
The mechanism by which an apparently uniform population of cells can generate a heterogeneous population of differentiated derivatives is a fundamental aspect of pluripotent and multipotent stem cell behaviour.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com