Combined with the cadence of the parasite lifecycle stages, and the behaviour and detailed cellular and molecular character of skinstage parasites during transmission, we define a novel immuno-epidemiological model for vaccine success/failure.
The gradient behaviour of the cellular structure provides additional complexity, and the possibility of tailoring design properties, such as the stiffness per unit of weight.
There is also a broader literature focussing on modelling self-organized behaviour at the cellular level (reviewed in [ 25]).
In systems biology, PSA has found wide applications, such as for model calibration and identifiability, model validation and reduction, identification of bottlenecking processes, elucidation of mechanisms of complex cellular behaviour, and investigation of cellular robustness [ 30, 33].
Precision, robustness and repeatability are thus restricted by day-to-day variability in cellular behaviour, changes in the cellular environment, and the typically limited quantitative understanding of the open-loop controlled system.
MRI sensitivity in the detection of Gd-labelled cells is lower compared to SPIO-labelled cells and is dependent upon contrast behaviour and relaxivity in the cellular compartment (endosomes) in which they are localised [ 47, 48].
The soft agar growth pattern is indicative of cellular behaviour and the profound phenotypic changes induced by LL-37 peptide treatment, most likely reflect an enhanced migratory and invasive capacity in these cells.
This paper presents the compared analysis of the foaming behaviour and cellular structure of LDPE/hectorite nanocomposites and respective neat LDPE foams.
As observed for other master transcriptional regulators of cell behaviour, the cellular response to p53 activation varies greatly with the context.
Thermoregulation requires the integration between environment, behaviour, and cellular function [2].
